Infidelity out in the open

1Citations
Citations of this article
6Readers
Mendeley users who have this article in their library.

Abstract

The crystal structures of DNA polymerase β in complex with two different mispairs (A-C and T-C) reveal that the two bases stack partially, rather than engage in hydrogen bonding with each other (Krahn et al., 2004, this issue of Structure). The N-domain of the polymerase, which is closed when the correct nucleotide pairs with the template base, adopts a partially open conformation suboptimal for catalysis.

Cite

CITATION STYLE

APA

Doublié, S. (2004). Infidelity out in the open. Structure. Cell Press. https://doi.org/10.1016/j.str.2004.09.002

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free