Influence of statistical variations in cell distribution on the proliferation kinetics of Madin-Darby canine kidney cells on quartz crystal resonator

0Citations
Citations of this article
8Readers
Mendeley users who have this article in their library.

Abstract

The influence of statistical variations in cell distribution on the proliferation of Madin-Darby canine kidney (MDCK-II) cells was analyzed. MDCK-II cells were cultivated in parallel on 4 quartz crystal resonators in a bioreactor chip. Results of proliferation experiments with different initial grade of confluence were compared. Light microscope pictures of the sensor surface and impedance spectra were continuously acquired. CFD simulation results of the bioreactor chip were employed to verify experimental conditions. Results show that especially at low confluency dissimilar development of non-confluent MDCK-II cell layers and resulting changes in acoustic load depend significantly on initial cell distribution. © 2009.

Cite

CITATION STYLE

APA

Cama, G., Bolaeva, K., Jacobs, T., Hartmann, M., Hirsch, S., Naumann, M., & Hauptmann, P. (2009). Influence of statistical variations in cell distribution on the proliferation kinetics of Madin-Darby canine kidney cells on quartz crystal resonator. In Procedia Chemistry (Vol. 1, pp. 373–376). https://doi.org/10.1016/j.proche.2009.07.093

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free