The recent progress in our understanding of how some proteins can recognize inositol lipids via specific binding domains, such as pleckstrin homology (PH) domains, has been put to a good practical use to measure these lipids in live cells in real time. But what are the limitations, and what are the ways forward?
Irvine, R. (2004, April 20). Inositol lipids: To PHix or not to PHix? Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2004.03.051