The Ins and Outs of Heterochromatic DNA Repair

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Abstract

Repetitive DNA is often packaged into heterochromatin structures that prevent illicit recombination events that cause genomic instability. A recent study by Chiolo et al. (2011) published in Cell finds that DNA double-strand breaks formed within heterochromatin are shuttled to adjacent sites that are " safe" to complete repair by recombination. © 2011 Elsevier Inc.

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Peterson, C. L. (2011, March 15). The Ins and Outs of Heterochromatic DNA Repair. Developmental Cell. https://doi.org/10.1016/j.devcel.2011.02.009

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