The composition of the tumor microenvironment is associated with a patient's prognosis and can be therapeutically targeted. A link between the cellular composition and genomic features of the tumor and its response to immunotherapy is beginning to emerge. Analyzing the microenvironment of tumor molecular subgroups can be a useful approach to tailor immunotherapies.
Becht, E., de Reyniès, A., & Fridman, W. H. (2015, November 14). Integrating tumor microenvironment with cancer molecular classifications. Genome Medicine. BioMed Central Ltd. https://doi.org/10.1186/s13073-015-0241-4