The interactions between integrins and the extracellular matrix have been identified as important regulators of vascular cell survival, proliferation and invasion during the complex process of blood vessel formation by angiogenesis.
Strömblad, S., & Cheresh, D. A. (1996). Integrins, angiogenesis and vascular cell survival. Chemistry and Biology. Elsevier Ltd. https://doi.org/10.1016/S1074-5521(96)90176-3