Melasma is difficult to treat. Vitamin C, topical and by iontophoresis, has been shown to be useful. When lasers are used, there is a significant incidence of post-laser hyperpigmentation. There is no single established treatment for the latter. The case history of a 51-year-old Chinese woman is presented. Intravenous vitamin C appears to be useful in treating this complication.
Lee, G. S. K. (2008). Intravenous vitamin C in the treatment of post-laser hyperpigmentation for melasma: A short report. Journal of Cosmetic and Laser Therapy, 10(4), 234–236. https://doi.org/10.1080/14764170802187193