??? Thrombocytosis is more often reactive than due to a primary haematological disorder. ??? Diagnosing the cause of thrombocytosis is important to enable appropriate management. ??? The cause of thrombocytosis can often be determined by reviewing previous full blood counts, considering any other abnormalities on the full blood count and taking a detailed history. ??? There are a small number of patients with thrombocytosis in whom the cause will remain uncertain. ??? Some laboratory tests may assist in difficult cases; however, there is none that will definitely differentiate reactive from autonomous thrombocytosis. ??? Patients with a primary haematological disorder and those in whom the diagnosis has not been determined should be referred to a haematologist.
Warburton, P., & Pokorny, C. S. (2005). Investigating thrombocytosis. Medicine Today, 6(1), 32. https://doi.org/10.1136/bmj.l4183