Exercise exerts beneficial effects on systemic metabolism. A recent Nature paper (Boström et al., 2012) identifies irisin as an exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin promotes brown adipocyte recruitment in white fat and improves systemic metabolism by increasing energy expenditure. © 2012 Elsevier Inc.
Villarroya, F. (2012, March 7). Irisin, turning up the heat. Cell Metabolism. https://doi.org/10.1016/j.cmet.2012.02.010