We have developed an iron (III) phthalocyanine chloride-catalyzed oxidation-aromatization of α, β-unsaturated ketones with hydrazine hydrate. Various 3,5-disubstituted 1H-pyrazoles were obtained in good to excellent yields. This method offers several advantages, including room-temperature conditions, short reaction time, high yields, simple work-up procedure, and use of air as an oxidant. The catalyst can be recovered and reused five times without loss of activity.
Zhao, J., Qiu, J., Gou, X., Hua, C., & Chen, B. (2016). Iron(III) phthalocyanine chloride-catalyzed oxidation-aromatization of α, β-unsaturated ketones with hydrazine hydrate: Synthesis of 3, 5-disubstituted 1H-pyrazoles. Cuihua Xuebao/Chinese Journal of Catalysis, 37(4), 571–578. https://doi.org/10.1016/S1872-2067(15)61043-9