In the February 21 issue of Cell, Liakopoulos et al. demonstrate that asymmetrical loading of Kar9 onto astral microtubules (MTs) emanating from the budward-directed spindle pole ensures delivery of this spindle pole to the bud. Kar9 mediates alignment of the spindle with the cell polarity axis through a Myo2-dependent mechanism that reorients astral MTs toward the bud.
Paoletti, A., & Bornens, M. (2003, March 1). Kar9 asymmetrical loading on spindle poles mediates proper spindle alignment in budding yeast. Developmental Cell. https://doi.org/10.1016/S1534-5807(03)00065-0