We describe functional simplified T cell and Fc receptor chimeras that are capable of directing CD8+ cytotoxic T lymphocytes (CTLs) to specifically recognize and lyse cells expressing HIV envelope proteins. Target cells bearing HLA-DR molecules are not recognized by CTL armed with the chimeras. The variety of cell types in which the native receptors are active suggests multiple possibilities for antiviral intervention through genetic means.
Spagnoletti, F. N., di Pardo, A. F., Tobar Gómez, N. E., & Chiocchio, V. M. (2013). Las micorrizas arbusculares y Rhizobium: Una simbiosis dual de interés. Revista Argentina de Microbiologia, 45(2), 131–132. https://doi.org/10.1016/S0325-7541(13)70012-9