In the current issue of Molecular Cell, de la Vega et al. (2012) propose an intriguing model for HIPK2 posttranslational modifications in response to oxidative stress, explaining how HIPK2 can possess both prosurvival as well as proapoptotic activities. © 2012 Elsevier Inc.
Chiocca, S., & Seiser, C. (2012, May 25). Lifting the Threshold between Life and Death: SUMO and HDAC Fine-Tune HIPK2 to Sense Redox Status. Molecular Cell. https://doi.org/10.1016/j.molcel.2012.05.010