Cerebral organoids represent a new model in which to study human brain development outside the human body. Recently in Nature Biotechnology, Lancaster et al. (2017) tackled the lack of reproducibility, tissue homogeneity, and complexity of this system by bioengineering organoids to establish the next generation of human mini brains.
Koch, P., & Ladewig, J. (2017, August 3). A Little Bit of Guidance: Mini Brains on Their Route to Adolescence. Cell Stem Cell. Cell Press. https://doi.org/10.1016/j.stem.2017.07.001