We report on our experience with the intra-arterial administration of eptifibatide for thrombolysis during aneurysm-embolization procedures. In 4 cases (3 stent-assisted coiling procedures and 1 with posthemorrhagic vasospasm), we noted the formation of thrombus occluding a vessel. We administered eptifibatide (10-15 mg) through a microcatheter proximal to the thrombus. The thrombus rapidly dissolved, resulting in the recanalization of the occluded vessels with no rethrombosis or hemorrhagic complications.
Katsaridis, V., Papagiannaki, C., Skoulios, N., Achoulias, I., & Peios, D. (2008). Local intra-arterial eptifibatide for intraoperative vessel thrombosis during aneurysm coiling. American Journal of Neuroradiology, 29(7), 1414–1417. https://doi.org/10.3174/ajnr.A1068