The lorazepam and diazepam protocol for catatonia due to general medical condition and substance in Liaison psychiatry

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Abstract

Objective: The lorazepam-diazepam protocol had been proved to rapidly and effectively relieve catatonia in patients with schizophrenia or mood disorder. This study aims to investigate the efficacy of lorazepam-diazepam protocol in catatonia due to general medical conditions (GMC) and substance. Method: Patients with catatonia that required psychiatric intervention in various settings of a medical center were included. The lorazepam-diazepam protocol had been used to treat the catatonia due to GMC or substance according to DSM-IVcriteria. The treatment response had been assessed by two psychiatrists. Results: Eighteen (85.7%) of 21 catatonic patients due to GMC or substance became free of catatonia after the lorazepam-diazepam protocol. Five (23.8%) of the 21 patients had passed away with various causes of death and wide range of time periods after catatonia. Conclusion: Our results showed that the lorazepam-diazepam protocol could rapidly and effectively relieve catatonia due to GMC and substance.

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Lin, C. C., Hung, Y. Y., Tsai, M. C., & Huang, T. L. (2017). The lorazepam and diazepam protocol for catatonia due to general medical condition and substance in Liaison psychiatry. PLoS ONE, 12(1). https://doi.org/10.1371/journal.pone.0170452

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