Macrophage Activation Syndrome: A Report of Two Cases and a Literature Review

  • Alkoht A
  • Hanafi I
  • Khalil B
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Abstract

Macrophage activation syndrome (MAS) is a severe, potentially fatal condition that may complicate autoimmune diseases, and it belongs to hemophagocytic lymphohistiocytosis (HLH) disorders. MAS occurs in adults and children. However, it is rare in juvenile systemic lupus erythematosus (jSLE), and it is extremely rare to be the initial presentation of jSLE. Here, we report two patients with juvenile SLE who initially presented with MAS. One of the two patients is 4 years old. This is the youngest reported patient to our knowledge.

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Alkoht, A., Hanafi, I., & Khalil, B. (2017). Macrophage Activation Syndrome: A Report of Two Cases and a Literature Review. Case Reports in Rheumatology, 2017, 1–5. https://doi.org/10.1155/2017/5304180

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