MALDI imaging: beyond classic diagnosis

1Citations
Citations of this article
16Readers
Mendeley users who have this article in their library.

Abstract

Mass spectrometry has been the focus of technology development and application for imaging for several decades. Imaging mass spectrometry using matrix-assisted laser desorption ionization is a new and effective tool for molecular studies of complex biological samples such as tissue sections. As histological features remain intact throughout the analysis of a section, distribution maps of multiple analytes can be correlated with histological and clinical features. Spatial molecular arrangements can be assessed without the need for target-specific reagents, allowing the discovery of diagnostic and prognostic markers of different cancer types and enabling the determination of effective therapies.

Author supplied keywords

Cite

CITATION STYLE

APA

Manzanares-Meza, L. D., Gutiérrez-Román, C. I., & Medina-Contreras, O. (2017, May 1). MALDI imaging: beyond classic diagnosis. Boletin Medico Del Hospital Infantil de Mexico. Masson-Doyma Mexico, S.A. https://doi.org/10.1016/j.bmhimx.2017.03.004

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free