The specificity of connections made by inhibitory interneurons in the neocortex is not well understood. In this issue of Neuron, Fino and Yuste (2011) use an enhanced version of two-photon glutamate uncaging, which preserves inhibitory synaptic transmission, to demonstrate that somatostatin-positive interneurons form densely convergent connections onto pyramidal cells in layer 2/3 of mouse frontal cortex. © 2011 Elsevier Inc.
Lee, C. K., & Huguenard, J. R. (2011, March 24). Martinotti cells: Community organizers. Neuron. https://doi.org/10.1016/j.neuron.2011.03.003