Immunoglobulin G4 (IgG4)-related diseases have been reported to be systemic diseases characterized by elevation of serum IgG4 concentration and infiltration of IgG4-positive plasma cells within the target organ. However, the involvement of coronary artery is very rare. Here, we report a 62-year-old man with mass lesions surrounding coronary artery and abdominal aorta associated with IgG4-related disease diagnosed by a needle biopsy of the mass lesion surrounding the coronary artery using echocardiography and computed tomography. After we started to treat the patient with prednisolone, his serum IgG4 level decreased, and the mass lesions of coronary and abdominal artery were markedly reduced in size after 4 months. In conclusion, IgG4-related disease should be considered in addition to tumors such as malignant lymphoma when mass lesions surrounding coronary artery are detected. © 2012 Japanese College of Cardiology.
Kusumoto, S., Kawano, H., Takeno, M., Kawahara, F., Abe, K., Hayashi, H., … Maemura, K. (2012). Mass lesions surrounding coronary artery associated with immunoglobulin G4-related disease. Journal of Cardiology Cases, 5(3). https://doi.org/10.1016/j.jccase.2012.02.006