The study of MSC trafficking is clinically relevant for minimally invasive cell therapy to promote regeneration of damaged tissue, to treat inflammation, and to promote angiogenesis. However, these studies are complicated by the diverse methods used to culture, characterize, and deliver MSCs and by the variety of methods used to assess homing events. This review provides a critical analysis of the methods used to track homing of exogenously infused MSCs and discusses strategies for enhancing their trafficking to particular tissues. © 2009 Elsevier Inc. All rights reserved.
Karp, J. M., & Leng Teo, G. S. (2009, March 6). Mesenchymal Stem Cell Homing: The Devil Is in the Details. Cell Stem Cell. https://doi.org/10.1016/j.stem.2009.02.001