Cells lacking a functional tuberous sclerosis complex (TSC) heterodimer are sensitized to glucose starvation-induced death. In this issue of Molecular Cell, Choo et al. (2010) report that reducing energy consumption allows these cells to survive on glutamine as an alternative energy source. © 2010 Elsevier Inc. All rights reserved.
Abraham, R. T., & Eng, C. H. (2010, May 28). A Metabolic (Re-)Balancing Act. Molecular Cell. https://doi.org/10.1016/j.molcel.2010.05.008