Metastatic Breast Cancer to the Gastrointestinal Tract: Report of Five Cases and Review of the Literature

  • Ambroggi M
  • Stroppa E
  • Mordenti P
  • et al.
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Abstract

Luminal gastrointestinal (GI) metastases from breast cancer are rare, reports are fragmentary and poor. The purposes of this study are to assess the gastrointestinal involvement from breast cancer in a retrospective study at a single institution and reviewing the related literature. Between January 2007 and December 2011 a total of 980 patients with breast cancer were treated at our institution, patients’ records and report database were analysed. Institutional Review Board approval was obtained for this study. A search of the literature using PubMed, CancerLit, Embase, was performed. Selected for the present review were papers published in English before June 2012. Five of 980 patients (0.5%) showed gastrointestinal metastases from breast cancer, 3 patients had gastric involvement, 1 jejunum, and 1 rectum. Reviewing the literature, 206 patients affected by gastrointestinal metastasis from breast cancer were identified: the most frequent site of metastasis was the stomach (60%). The majority of the patients underwent chemotherapy and endocrine therapy, someone surgery and radiotherapy. GI metastases from breast cancer are rare, but possible, and a very late recurrence can also occur. Cyto-histological diagnosis is mandatory, to differentiate GI metastases from breast cancer to other diseases and to allow an adequate treatment.

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APA

Ambroggi, M., Stroppa, E. M., Mordenti, P., Biasini, C., Zangrandi, A., Michieletti, E., … Cavanna, L. (2012). Metastatic Breast Cancer to the Gastrointestinal Tract: Report of Five Cases and Review of the Literature. International Journal of Breast Cancer, 2012, 1–8. https://doi.org/10.1155/2012/439023

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