Of mice and men: What physiological correlates of cognitive deficits in a mouse model of schizophrenia tell us about psychiatric disease

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Abstract

Hippocampal neurons "replay" activity related to previous events during rest. In this issue of Neuron, Suhetal. (2013) show that this physiological correlate of learning is impaired in mice lacking calcineurin, establishing a link between synaptic anomalies and cognitive deficits observed in this schizophrenia model

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O’Donnell, P. (2013, October 16). Of mice and men: What physiological correlates of cognitive deficits in a mouse model of schizophrenia tell us about psychiatric disease. Neuron. https://doi.org/10.1016/j.neuron.2013.10.012

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