Microprocessor-controlled movement of solid gastric content using sequential neural electrical stimulation

Citations of this article
Mendeley users who have this article in their library.


Background and Aims: Gastric electrical stimulation has been attempted for years without much success. The aim of this study was to determine if movement of solid gastric content could be achieved using microprocessor- controlled sequential electrical stimulation. Methods: The study was performed on 9 anesthetized dogs. The dogs underwent laparotomy, pyloroplasty, and implantation of 4-6 sets of bipolar stainless-steel wire electrodes. Each set consisted of 2-6 electrodes (10 x 0.25 mm, 3 cm apart) implanted circumferentially. The stomach was filled with solid food mixed with plastic pellets, and the process of gastric emptying was monitored. Artificial contractions were produced using microprocessor-controlled phase- locked bipolar trains of 50-Hz rectangular voltage with flexible amplitudes. Results: Using the above stimulating parameters, we were able to produce circumferential gastric contractions that were artificially propagated distally by embedding and phase-locking the stimulating voltage. The number of expelled pellets after the stimulation sessions was significantly higher than the number of pellets emptied during the nonstimulation sessions (P<0.01). Conclusions: Microprocessor-controlled electrical stimulation produced artificial peristalsis and markedly accelerated the movement of solid gastric content.




Mintchev, M. P., Sanmiguel, C. P., Amaris, M., & Bowes, K. L. (2000). Microprocessor-controlled movement of solid gastric content using sequential neural electrical stimulation. Gastroenterology, 118(2), 258ā€“263. https://doi.org/10.1016/S0016-5085(00)70207-1

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free