MicroRNA Pathways in Flies and Worms

  • Ambros V
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Abstract

Drosophila geneticists have uncovered roles for microRNAs in the coordination of cell proliferation and cell death during development, and in stress resistance and fat metabolism. In C. elegans, a homolog of the well-known fly developmental regulator hunchback acts downstream of the microRNAs lin-4 and let-7 in a pathway controlling developmental timing.

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Ambros, V. (2004). MicroRNA Pathways in Flies and Worms. Cell, 113(6), 673–676. https://doi.org/10.1016/s0092-8674(03)00428-8

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