Microstructural parcellation of the human cerebral cortex - from Bbrodmann's post-mortem map to in vivo mapping with high-field magnetic resonance imaging

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Abstract

The year 2009 marked the 100th anniversary of the publication of the famous brain map of Korbinian Brodmann. Although a "classic" guide to microanatomical parcellation of the cerebral cortex, it is - from today's state-of-the-art neuroimaging perspective - problematic to use Brodmann's map as a structural guide to functional units in the cortex. In this article we discuss some of the reasons, especially the problematic compatibility of the "post-mortem world" of microstructural brain maps with the "in vivo world" of neuroimaging. We conclude with some prospects for the future of in vivo structural brain mapping: a new approach which has the enormous potential to make direct correlations between microstructure and function in living human brains: "in vivo Brodmann mapping" with high-field magnetic resonance imaging. © 2011 Geyer, Weiss, Reimann, Lohmann and Turner.

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Geyer, S., Weiss, M., Reimann, K., Lohmann, G., & Turner, R. (2011). Microstructural parcellation of the human cerebral cortex - from Bbrodmann’s post-mortem map to in vivo mapping with high-field magnetic resonance imaging. Frontiers in Human Neuroscience, (FEBRUARY), 1–7. https://doi.org/10.3389/fnhum.2011.00019

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