In this issue of Immunity, Shulman et al. (2009) describe shear-facilitated chemokine-induced adhesive filopodia on crawling T lymphocytes that scan the endothelial surface for potential sites of transendothelial migration. These filopodia facilitate a novel millipede-like mode of lymphocyte locomotion over endothelial cells prior to extravasation. © 2009 Elsevier Inc. All rights reserved.
Ward, S. G. (2009, March 20). Millipede-like Lymphocyte Crawling: Feeling the Way with Filopodia. Immunity. https://doi.org/10.1016/j.immuni.2009.03.002