Although many microRNAs (miRNAs) and their targets have been identified, the importance of miRNAs in vivo is still unclear. In this issue, Zhao et al. (2007) generate mice deficient in a cardiac-specific miRNA, miR-1-2, and reveal that this microRNA plays a crucial role in heart development and physiology. © 2007 Elsevier Inc. All rights reserved.
Mishima, Y., Stahlhut, C., & Giraldez, A. J. (2007, April 20). miR-1-2 Gets to the Heart of the Matter. Cell. https://doi.org/10.1016/j.cell.2007.04.008