Use of miRNAs in biofluids as biomarkers in dietary and lifestyle intervention studies

11Citations
Citations of this article
38Readers
Mendeley users who have this article in their library.

Abstract

The selection of biomarkers in nutrigenomics needs to reflect subtle changes in homoeostasis representing the relation between nutrition and health, or nutrition and disease. It is believed that noncoding RNAs, such as circulating microRNAs (miRNAs), may represent such a new class of integrative biomarkers. Until now, the most relevant body fluids for miRNA quantification in response to nutrition have not been clearly defined, but recent studies listed in this review indicate that miRNAs from plasma or serum, PBMC and faeces might be relevant biomarkers to quantify the physiological impacts of dietary or lifestyle intervention studies. In addition, a number of recent studies also indicate that miRNAs could permit to monitor the impact of diet on gut microbiota. We also discuss the main preanalytical considerations that are important to take into account before miRNA screening which can affect the reproducibility of the data.

Cite

CITATION STYLE

APA

Rome, S. (2015, September 6). Use of miRNAs in biofluids as biomarkers in dietary and lifestyle intervention studies. Genes and Nutrition. Springer Verlag. https://doi.org/10.1007/s12263-015-0483-1

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free