Mixed acid-base disorders, hydroelectrolyte imbalance and lactate production in hypercapnic respiratory failure: The role of noninvasive ventilation

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Abstract

Hypercapnic Chronic Obstructive Pulmonary Disease {(COPD)} exacerbation in patients with comorbidities and multidrug therapy is complicated by mixed acid-base, hydro-electrolyte and lactate disorders. Aim of this study was to determine the relationships of these disorders with the requirement for and duration of noninvasive ventilation {(NIV)} when treating hypercapnic respiratory failure.

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Terzano, C., Di Stefano, F., Conti, V., Di Nicola, M., Paone, G., Petroianni, A., & Ricci, A. (2012). Mixed acid-base disorders, hydroelectrolyte imbalance and lactate production in hypercapnic respiratory failure: The role of noninvasive ventilation. PLoS ONE, 7(4). https://doi.org/10.1371/journal.pone.0035245

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