MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content

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Abstract

MLN64 is a late endosomal cholesterol-binding membrane protein that has been implicated in cholesterol transport from endosomal membranes to the plasma membrane and/or mitochondria, in toxin-induced resistance

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Balboa, E., Castro, J., Pinochet, M. J., Cancino, G. I., Matías, N., José Sáez, P., … Zanlungo, S. (2017). MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content. Redox Biology, 12, 274–284. https://doi.org/10.1016/j.redox.2017.02.024

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