Because of its fast image acquisition and the rich diagnostic information it provides, computed tomography (CT) has gradually become a popular imaging modality among clinicians. Because CT scanners emit x-rays, the increased use of CT in clinical applications inevitably leads to increased medical radiation dose to the population. Because of the well-known cancer-inducing effects of high dose x-ray radiation, this increased dose has caused concerns among policy makers and general public that CT patients may be at a higher risk of developing cancer. Over the years, CT manufacturers have developed a variety of strategies to address this issue, the latest being a model-based iterative reconstruction (MBIR) algorithm. MBIR is an advanced CT algorithm that incorporates modeling of several key parameters that were omitted in earlier algorithms to reduce computational requirement and speed up scans. This review article examines the latest literature in the clinical CT field and discusses the general principles of MBIR, its dose and noise reduction potentials, its imaging characteristics, and its limitations. MBIR algorithm and its application in today's CT imaging will greatly reduce the radiation dose to patients and improve image quality for clinicians. © 2014 Elsevier Inc. All rights reserved.
Liu, L. (2014). Model-based iterative reconstruction: A promising algorithm for today’s computed tomography imaging. Journal of Medical Imaging and Radiation Sciences, 45(2), 131–136. https://doi.org/10.1016/j.jmir.2014.02.002