Molecular biomarker analyses using circulating tumor cells

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Abstract

Evaluation of cancer biomarkers from blood could significantly enable biomarker assessment by providing a relatively non-invasive source of representative tumor material. Circulating Tumor Cells (CTCs) isolated from blood of metastatic cancer patients hold significant promise in this regard.

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Punnoose, E. A., Atwal, S. K., Spoerke, J. M., Savage, H., Pandita, A., Yeh, R. F., … Lackner, M. R. (2010). Molecular biomarker analyses using circulating tumor cells. PLoS ONE, 5(9), 1–12. https://doi.org/10.1371/journal.pone.0012517

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