Molecular Phylogeny of Suid Herpesvirus 1

  • Fonseca A
  • Sales É
  • Heinemann M
  • et al.
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Abstract

Pseudorabies is a disease that significantly impacts the swine industry. This disease is caused by Suid Herpesvirus 1 (SuHV-1), which is a double-stranded DNA virus that belongs to the Herpesviridae family and the Alphaherpesvirinae subfamily and exhibits a slow rate of genetic evolution. The aim of this study was to use both full and partial sequences of SuHV-1 genes available in GenBank to examine the evolution and divergence of viruses isolated in different parts of the world. Partial and complete sequences of SuHV-1 genes were obtained either from GenBank (i.e., us6 , us7 , us8 , us9 , ul14 , ul49.5 , and ul44 ) or from genetic sequencing of Brazilian SuHV-1 samples. The results of this study corroborate previous phylogenetic studies of SuHV-1 that demonstrated different evolutionary profiles of isolates from different parts of the globe, with a rapid genetic dispersion of Chinese isolates. All of the phylogenetic trees generated in this study demonstrated a large genetic distance between SuHV-1 isolates from the Western and Eastern regions of the world.

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Fonseca, A. A., Sales, É. B., Heinemann, M. B., & Reis, J. K. P. (2014). Molecular Phylogeny of Suid Herpesvirus 1. ISRN Virology, 2014, 1–7. https://doi.org/10.1155/2014/463173

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