Mitochondrial transport in neurons and their spatial distribution among synapses are directly correlated with synaptic activity. One paper in this issue of Neuron (MacAskill et al.) and two papers recently published in Cell (Wang and Schwarz) and PNAS (Saotome et al.) provide compelling evidence that Miro serves as a calcium sensor that controls mitochondrial mobility. © 2009 Elsevier Inc. All rights reserved.
Cai, Q., & Sheng, Z. H. (2009, February 26). Moving or Stopping Mitochondria: Miro as a Traffic Cop by Sensing Calcium. Neuron. https://doi.org/10.1016/j.neuron.2009.02.003