The increasing number of genes relevant to non–small-cell lung cancer treatment, combined with small lung tissue samples, has heightened the need for tissue stewardship to enable multiple biomarker testing. The present retrospective analysis evaluated 3659 single-gene tests across 1402 clinician-submitted samples and 169 investigational Oncomine Dx Target Tests. Compared with single-gene testing, the Oncomine Dx Target Test could facilitate successful multiple biomarker testing of small samples.
Yu, T. M., Morrison, C., Gold, E. J., Tradonsky, A., & Layton, A. J. (2019). Multiple Biomarker Testing Tissue Consumption and Completion Rates With Single-gene Tests and Investigational Use of Oncomine Dx Target Test for Advanced Non–Small-cell Lung Cancer: A Single-center Analysis. Clinical Lung Cancer, 20(1), 20-29.e8. https://doi.org/10.1016/j.cllc.2018.08.010