Myocardial infarction associated with thyrotoxicosis

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A thyroid storm--a sudden, life-threatening exacerbation of thyrotoxicosis--can lead to multiple organ failure due to hyperactivity of the sympathetic nervous system. Symptoms may include fever, tachycardia, cardiovascular collapse, myocardial infarction, hepatic failure, cerebral infarction, delirium, coma, and rhabdomyolysis. Various therapies have been proposed for the management of thyrotoxicosis. They include: reduction of sympathetic outflow (beta-blockers); decreased production and release of thyroid hormone (thiamazole, propylthiouracyl, or iodine solution); and peripheral conversion of T4 to T3 (beta-blockers and steroids).




Proskey, A. J., Saksena, F., & Towne, W. D. (1977). Myocardial infarction associated with thyrotoxicosis. Chest, 72(1), 109–111.

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