A new class of yeast transcriptional activators

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We describe yeast transcriptional activators encoded by E. coli genomic DNA fragments fused to the coding sequence of the DNA-binding portion of GAL4. All of the new activating sequences that we have analyzed, like those of GAL4 and GCN4, are acidic; most of these sequences show no obvious sequence homology when compared with the identified activating regions of GAL4 and GCN4 or among themselves. We also describe a fusion protein that contains no yeast protein sequence but activates transcription in yeast. © 1987.




Ma, J., & Ptashne, M. (1987). A new class of yeast transcriptional activators. Cell, 51(1), 113–119. https://doi.org/10.1016/0092-8674(87)90015-8

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