The nucleotide sequence of the gene cluster for the dissimilatory sulfite reductase (Dsr) from the Gram-negative thermophilic sulfate reducer Thermodesulforhabdus norvegica was determined. The Dsr-encoding genes (dsrAB) were found to be located in an operon encompassing four other open reading frames in the following order: dsrD-dsrA-dsrB-dsrN-dsrC-fdx. Localization of these six genes in the same operon supports previous suggestions that dsrD, -C and -N play essential roles in the mechanism for reduction of sulfite to sulfide. Transcriptional analysis showed that these genes constitute a contiguous transcriptional unit of at least 5 kb. The phylogeny of Dsr is discussed. © 2001 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
Larsen, Ø., Lien, T., & Birkeland, N. K. (2001). A novel organization of the dissimilatory sulfite reductase operon of Thermodesulforhabdus norvegica verified by RT-PCR. FEMS Microbiology Letters, 203(1), 81–85. https://doi.org/10.1016/S0378-1097(01)00337-8