'Ondine's Curse' is a rare syndrome consisting of chronic alveolar hypoventilation related to disturbances of brain system respiratory nuclei. Its clinical presentation is a sort of sleep induced apnea, eventually leading to chronic progressive involvement of cardiorespiratory apparatus. This paper reports a case of such a disease occurring without apparent cause in a 60-year-old woman. The pathogenesis and pathophysiology are discussed as well as the clinical-therapeutic implications.
Schwartz, B. A. (1976, September 25). ONDINE’S CURSE. The Lancet. https://doi.org/10.1016/S0140-6736(76)92516-2