Optimizing prescription of Chinese herbal medicine for unstable angina based on partially observable Markov decision process

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Abstract

<p> <italic>Objective</italic> . Initial optimized prescription of Chinese herb medicine for unstable angina (UA). <italic>Methods</italic> . Based on partially observable Markov decision process model (POMDP), we choose hospitalized patients of 3 syndrome elements, such as <italic>qi</italic> deficiency, blood stasis, and turbid phlegm for the data mining, analysis, and objective evaluation of the diagnosis and treatment of UA at a deep level in order to optimize the prescription of Chinese herb medicine for UA. <italic>Results</italic> . The recommended treatment options of UA for <italic>qi</italic> deficiency, blood stasis, and phlegm syndrome patients were as follows: Milkvetch Root + Tangshen + Indian Bread + Largehead Atractylodes Rhizome ( <math id="M1"> <mtext>ADR</mtext> <mo>=</mo> <mn>0.96630</mn> </math> ); Danshen Root + Chinese Angelica + Safflower + Red Peony Root + Szechwan Lovage Rhizome Orange Fruit ( <math id="M2"> <mtext>ADR</mtext> <mo>=</mo> <mn>0.76</mn> </math> ); Snakegourd Fruit + Longstamen Onion Bulb + Pinellia Tuber + Dried Tangerine peel + Largehead Atractylodes Rhizome + Platycodon Root ( <math id="M3"> <mtext>ADR</mtext> <mo>=</mo> <mn>0.658568</mn> </math> ). <italic>Conclusion</italic> . This study initially optimized prescriptions for UA based on POMDP, which can be used as a reference for further development of UA prescription in Chinese herb medicine. </p>

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Feng, Y., Qiu, Y., Zhou, X., Wang, Y., Xu, H., & Liu, B. (2013). Optimizing prescription of Chinese herbal medicine for unstable angina based on partially observable Markov decision process. Evidence-Based Complementary and Alternative Medicine, 2013. https://doi.org/10.1155/2013/532534

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