Osteogenesis imperfecta type I: A case report

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A 15-year-old male patient was admitted to hospital having experienced repeated fractures over the previous three years, predominantly due to falling down or overexertion. The clinical signs and radiological features, such as recurrent fractures, blue sclera and low bone mineral density (BMD) level, all led to the diagnosis of a mild form of osteogenesis imperfecta (OI) type I. The patient began treatment with a regular intake of calcium (1,000 mg/day), an adequate intake of vitamin D (800 U/day) and intravenous pamidronate (60 mg). Following four months of treatment, the symptoms and quality of life of the patient improved. This patient appears to be a rare case of OI type I.




Ren, J., Xu, X., Jian, X., & Wang, J. (2014). Osteogenesis imperfecta type I: A case report. Experimental and Therapeutic Medicine, 7(6), 1535–1538. https://doi.org/10.3892/etm.2014.1653

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