Pathogenesis of psoriasis and psoriatic arthritis

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Abstract

The pathophysiology of psoriasis is multifaceted and dynamic, involving a complex interplay between constitutive cells of the skin and the innate and adaptive immune systems. Until the early 1980s, psoriasis was considered to be primarily a disease of epidermal keratinocyte proliferation, with the cutaneous inflammatory infiltrate a secondary consequence.

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Coates, L., Savage, L., & Emery, P. (2016). Pathogenesis of psoriasis and psoriatic arthritis. In Handbook of Psoriasis and Psoriatic Arthritis (pp. 7–16). Springer International Publishing. https://doi.org/10.1007/978-3-319-18227-8_2

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