PET/CT in initial staging and therapy response assessment of lymphoma

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Objective To detect accuracy of PET/CT in the initial staging, response during the course and end of treatment in lymphoma patients compared to contrast CT. Materials and methods We studied 50 patients divided into 3 groups with pathologically proven lymphoma with a mean age = 27. All patients performed CT and PET/CT for initial staging, during the course of chemotherapy and at the end of treatment. Results PET/CT and CECT were agreeable in 75% of cases. 61% during treatment and41% agreement at the end of treatment. Conclusion PET/CT proved higher sensitivity and specificity over CECT. The major strength of PET/CT over CECT was its higher ability for detection of extra-nodal sites of lymphoma and excluding active disease in residual nodal mass lesions on follow-up.

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Omar, N. N., Alotaify, L. M., & Abolela, M. S. (2016). PET/CT in initial staging and therapy response assessment of lymphoma. Egyptian Journal of Radiology and Nuclear Medicine, 47(4), 1639–1647.

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