Placental abnormalities and preeclampsla in trisomy 13 pregnancies

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Abstract

Women who are carrying a trisomy 13 fetus are prone to have an abnormal placenta as well as to develop preeclampsia in the second and third trimesters. This article provides a comprehensive review of placental abnormalities, such as small placental volume, reduced placental vascularization, a partial molar appearance of the placenta and placental mesenchymal dysplasia, and preeclampsia associated with trisomy 13 pregnancies. The candidate preeclampsia-causing genes on chromosome 13, such as sFlt1, COL4A2 and periostin, are discussed.

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APA

Chen, C. P. (2009). Placental abnormalities and preeclampsla in trisomy 13 pregnancies. Taiwanese Journal of Obstetrics and Gynecology. Elsevier (Singapore) Pte Ltd. https://doi.org/10.1016/S1028-4559(09)60028-0

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