It is currently not known whether caffeine has an enhancing effect on long-term memory in humans. We used post-study caffeine administration to test its effect on memory consolidation using a behavioral discrimination task. Caffeine enhanced performance 24 h after administration according to an inverted U-shaped dose-response curve; this effect was specific to consolidation and not retrieval. We conclude that caffeine enhanced consolidation of long-term memories in humans. © 2014 Nature America, Inc. All rights reserved.
Borota, D., Murray, E., Keceli, G., Chang, A., Watabe, J. M., Ly, M., … Yassa, M. A. (2014). Post-study caffeine administration enhances memory consolidation in humans. Nature Neuroscience, 17(2), 201–203. https://doi.org/10.1038/nn.3623