Background: In era of multiple drug resistant organisms and HIV/AIDS, major problem of present day is to control hospital acquired infections (HAI). Major mode of HAI is spread of microbes through contaminated hands of health care providers. Therefore it is mandatory to either wash hands with antiseptic soap and water or alcohol based hand rub or change gloves in between patients. But in developing country like India where number of patients per doctor or nurse are very high, financial restrictions, lack of strict regulations and sometimes due to urgency of situation, there is tendency of hospital staff to avoid changing gloves in between patients. Further they can not use alcohol based hand rub over gloves because it is not recommended due to chemical incompatibility. Therefore we evaluated efficacy of alcohol based hand rub over bare hands and hands wearing latex gloves. Methods: Hands of ten healthy volunteers were contaminated with 2 ml overnight broth culture of Escherichia coli ATCC25922 and baseline level were determined by glove juice technique. Following a single hand rub, using 70% ethanol, count of surviving bacteria was done. Log10 reductions from baseline were calculated. Same procedure was repeated on hands with gloves. Results: There was no significant difference in efficacy of alcohol hand rub over hands with or without gloves (2.7 and 2.68 Log10 reduction of bacterial load respectively). We also checked effect of alcohol hand rub on porosity of latex gloves and found that even after 3 hours of regular use and frequent alcohol rub, latex gloves did not become porous to permit transmigration of Escherichia coli ATCC25922 through its surface. Conclusion: Alcohol hand rub is equally effective on gloves and it is better to use alcohol rub over gloves to attend every patient without changing them. Further there is need to develop better gloves made of an alcohol compatible material.
Jain, S., Sharma, D., & Dhole, T. N. (2011). PP-229 Role of alcohol based hand rub on latex gloves for prevention of hospital acquired infections. International Journal of Infectious Diseases, 15, S108. https://doi.org/10.1016/s1201-9712(11)60379-2