Epidermal growth factor receptor (EGFR) signaling is instrumental for terminal differentiation of keratinocytes, hair morphogenesis, and maintenance of the skin barrier. Cheng et al. (2010) now demonstrate that the calcium-permeable channel TRPV3 is required for these EGFR-dependent functions. © 2010 Elsevier Inc.
Montell, C. (2010, April). Preventing a perm with TRPV3. Cell. https://doi.org/10.1016/j.cell.2010.03.043