Prophenin-1, an exceptionally proline-rich antimicrobial peptide from porcine leukocytes

76Citations
Citations of this article
22Readers
Mendeley users who have this article in their library.

Abstract

We purified and characterized an unusual antimicrobial peptide, prophenin-1 (PF-1), from porcine leukocytes. The peptide had a mass of 8,683 and contained 79 residues, including 42 (53.2%) prolines and 15 (19.0%) phenylalanines. Its N-terminal 60 residues consisted of three perfect and three nearly perfect repeats of a decamer, FPPPNFPGPR. Prophenin-1 was encoded on a cathelin-containing precursor and showed substantially more activity against E. coli, a Gram-negative bacterium, than against Listeria monocytogenes, a Gram-positive organism, in vitro. © 1995.

Cite

CITATION STYLE

APA

Harwig, S. S. L., Kokryakov, V. N., Swiderek, K. M., Aleshina, G. M., Zhao, C., & Lehrer, R. I. (1995). Prophenin-1, an exceptionally proline-rich antimicrobial peptide from porcine leukocytes. FEBS Letters, 362(1), 65–69. https://doi.org/10.1016/0014-5793(95)00210-Z

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free